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Shares of Revolution Summit rise as cancer drugs that have been tested show promise in improving survival rates

Shares of Revolution Medicines, Summit Therapeutics and Summit Therapeutics rose in premarket trading Monday after their experimental cancer treatment boosted'survival rates for patients' in late-stage clinical trials.

Daraxonrasib is an experimental cancer pill that doubles survival when compared with chemotherapy. Summit's ivonescimab treatment, in collaboration with Akeso, a Chinese partner, helped lung cancer patients to live 15 percent longer than BeOne Medicines Tevimbra.

On Sunday, the companies presented their data at the American Society of Clinical Oncology in Chicago.

Summit's stock gained 3.6%, while Revolution's shares rose 7.3%. Summit's shares are essentially flat this year while Revolution's has almost doubled.

Daraxonrasib was found to reduce the risk of death in patients with advanced pancreatic carcinoma who had already failed a round of chemotherapy by 60% compared to chemotherapy standard.

Two?brokers called Revolution's trial data "compelling." Sean McCutcheon, Raymond James analyst, called the overall survival results of daraxonrasib a "homerun" and predicted rapid and widespread adoption in patients with advanced cancer.

Patients with advanced non-small-cell lung cancer treated with ivonescimab, chemotherapy and Tevimbra lived on average 27.9 months compared to 23.7 months in the Tevimbra-treated group.

Tyler Van 'Buren, TD 'Cowen analyst, said: "This is a significant advancement in a -setting where other treatments have never found success."

Summit has the rights to the drug for the U.S.A., Canada Europe and Japan, through a deal worth up to $5 billion. Akeso holds the rights in?China and for the rest of world.

Some analysts warned that there are still questions about the broader patient populations and whether or not this?study is applicable to China only.

Faisal Khurshid, an analyst at Jefferies, said that investors will be looking to see if similar benefits are replicated globally in trials conducted in the U.S.A. and Europe. Reporting by Christy Santhosh from Bengaluru, edited by Pooja Deai and Sriraj Kalluvila

(source: Reuters)