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Wildfire smoke exposure may shorten lung cancer survival

A large California study, presented on Saturday at a major medical conference, found that exposure to wildfire smoke can increase the risk of lung cancer patients dying, especially among non-smokers. However, certain cancer treatments may mitigate this effect.

Researchers followed up on more than 18000 people diagnosed with non-small-cell lung cancer, the most common type of lung cancer. This was between 2017 and 2020. Researchers found that those who lived in areas with high levels of air pollution caused by wildfires in the first year following their cancer diagnosis had a higher risk of dying from the disease.

Researchers reported that patients who inhaled high levels of small particulate matter, with a diameter of less than 2.5 microns and can penetrate deep into the lungs, had a 20% higher risk of lung cancer death.

Researchers found that people with advanced cancer stage 4 who have never smoked are particularly affected. Researchers found that their risk of death from cancer increased by 55% if they were exposed high levels of air pollution caused by wildfires.

This study relied on advanced modeling to estimate the daily air quality of patients' homes, using data from satellites. weather models, smoke predictions, and air quality monitors.

Researchers also found that wildfire exposure did not have a significant impact on the survival of Stage 4 lung cancer patients who had smoked in the past and were being treated with immunotherapy drugs.

Researchers said that this surprising trend indicates that changes caused by smoking in the body could interact with certain treatments. Further study is needed to understand this phenomenon.

Smoke from wildfires is more toxic than air pollution. It contains soil particles, biological materials and traces of metals, plastics, and other synthetic materials.

Surbhi Singhal, a researcher at the UC Davis Comprehensive Cancer Center, Sacramento, California, said: "As wildfires are becoming more intense and frequent in California and elsewhere in the U.S. we need to develop targeted health strategies that protect cancer patients as well as those with other serious health issues." Reporting by Nancy Lapid, Editing by Bill Berkrot

(source: Reuters)